Pigmentary Disorder (Lentigo / Melasma / Vitiligo / Hyperpigmentation / Hypopigmentation), Control of melanogenesis, Melanocyte biology

Department of Dermatology (임상)

3D cell culture in nanofibrous scaffold

Department of Pharmacology (기초/연구센터)

Antibody display/engineering, Anti-viral and anti-cancer functions of anti-nucleic and antibody

Department of Microbiology (기초/연구센터)

Axonal regeneration and plasticity in CNS injury, Modulation of microenvironment for neural stem cell transplantation, Degeneration and regeneration of the white matter in vascular dementia animal model

Department of Brain Science and Neurology (기초/연구센터)

Molecular mechanism of tumor necrosis factor-induced signaling, Necroptosis and Inflammation, Circulation Tumor Cells and clinical implication, Exploring of cell death and autophagy pathways in diseases

Department of Biochemistry & Molecular Biology (기초/연구센터)

Molecular mechanism of circadian clock, Crosstalk between metabolism and circadian clock (Role of O-GlcNAcylation in circadian clock), Role of circadian clock in neurodegenerative diseases, Human disease modelling using Drosphila

Department of Brain Science (기초/연구센터)

Tumor suppressor genes; Molecular mechanisms of the Hippo pathway in organ size control and tumorigenesis, Identification of novel targets for cancer therapy, Genomic instability and cancer

Genomic Instability Research Center (기초/연구센터)

Pharmacoepidemiology, Drug-drug interaction, Drug Repositioning, Medical Informatics, Biomedical-Knowledge Discovery

Department of Medical Informatics (기초/연구센터)

Physiologic function of Familial Parkinson’s disease-associated proteins such as α-synuclein, DJ-1, Parkin, PINK1, LRRK2 and UCH-L1, Pathophysiology of Parkinson’s disease, Roles of neuroinflammation on Neurodegenerative diseases, Pathophysiology of ROS-associated disorders such as asthma and noise-induced hearing loss

Department of Pharmacology (기초/연구센터)

Role of TIM-3 in T cell function in a tumor model

Regulation of TIM-3 expression

Pathogenesis of Behcet’s disease

Mechanisms underlying cytotoxic effect of silver nanoparticles

Department of Microbiology (기초/연구센터)

Carcinogenesis, Aging and Cancer, Skin Pigmentation

Department of Biochemistry & Molecular Biology (기초/연구센터)

Genetics and pharmacogenetics of ASA related allergy : ASA intolerant asthma and urticaria/angiodema, Pathogenic mechanisms of severe asthma and occupational asthma, Identification of new allergen and development of IgE detecting system, Mechanism of allergen Immunotherapy, Participated in many global clinical trials from phase II-IV in mild to severe asthma with GSK, Astra-Zeneka, Nycomed, Behringer Ingelheim and MSD.

Department Allergy (임상)

류마티스질환, 강직성척추염, 루푸스, 통풍

Department of Rheumatology (임상)

Development of stem cell therapies for stroke and brain tumors, Transcriptional regulation of the brain development, Role of Go proteins in the central nervous system

Department of Anatomy (기초/연구센터)

Herpes simplex virus induced inflammation in a mouse model, Inflammation related mechanism, Therapeutic target for inflammation, Mouse model for Behcet's disease, Electron microscopy

Department of Microbiology (기초/연구센터)

Pathogenesis for brain invading free-living amoebae

Inflammasome gene search on pathogenic free-living amoebae

Diagnostic monoclonal antibodies production for Malaria /dengue fever/ influenza virus

Department of Microbiology (기초/연구센터)

Treg regulation in autoimmune diseases,

Molecular mechanism of arthritis

Department of Pharmacology (기초/연구센터)

Cell senescence and cell transformation, Cellular energy metabolism and related signaling, Mitochondrial energy metabolism, Mitochondrial dynamics and biogenesis

Department of Biochemistry & Molecular Biology (기초/연구센터)

Deep learning-based clinical data and bio signal analysis

New drug discovery using clinical and drug big data

Nationwide medical data analysis (HIRA or NHIC data)

Department of Medical Informatics (기초/연구센터)

Diabetes : Pathogenesis of Type 2 DM, Obesity and Insulin Resistance

Department of Endocrinology & Metabolism (임상)

Roles for membrane lipids, phosphoinositides and their metabolizing enzymes in the regulation of cell signaling

Molecular mechanisms of membrane remodeling processes (ex, vesicle trafficking, autophagy)

Metabolism and function of lipids related to neurodegenerative disorders

Lipid-protein interaction

Lipid imaging and analysis

Chronic Inflammatory Disease Research Center (기초/연구센터)

Mitosis, Genomic instability, Growth factor signaling

Department of Biochemistry (기초/연구센터)

Neurointervention treatment for acute ischemic stroke

Chronic vascular impairment mode

Cerebral blood flow and energy metabolism in vivo

Translation of astrocyte role in clinical practices

Application of data mining for predicting various outcome in patients with acute ischemic stroke

Department of Neurology (임상)

Autophagy and Human Diseases

Department of Brain Science (기초/연구센터)

Molecular and cellular basis of human genetic disease, Candidate-gene and genome-wide association studies for complex traits, Mtiochondrial morphological dynamics in health and disease

Department of Medical Genetics (기초/연구센터)

Role of gap junctional intercellular communication and connexins in hearing, The mechanism of hair cell damage and protection, Tissue engineering and stem cells, Molecular biology of genetic hearing loss, Middle ear disease cholesteatoma, otitis media with effusion

Department of Otolaryngology (임상)

Biomarker discovery for hepatocellular carcinoma, Liquid biopsy (exosomal, cell free DNA ) for hepatocellular carcinoma, 

Department of Gastroenterology (임상)

Functions of glia in intact and injured brain, Neural stem cell proliferation and differentiation in intact and injured brain, Functions of glia and neural stem cells regulated by Parkinson's disease related genes

Department of Pharmacology & Brain Science (기초/연구센터)

Cell cycle and genomic instability, Mitochondria dynamics and protein quality control

Department of Biochemistry (기초/연구센터)

Molecular mechanisms of various cancer cell death modes (autophagic cell death, paraptosis, cell death through mitotic catastrophe, entosis, and apoptosis), Therapeutic strategies to selectively kill cancer cells

Department of Biochemistry and Molecular Biology (기초/연구센터)

Tumor microenvironments, Gastroinestinal malignancy, Cancer-associated fibroblast

Department of Surgery (임상)

Ischemic stroke, Cerebral blood flow control by using cerebral hemodynamics, Collateral circulation reservation for the brain protection, Neovasculogenesis for atherosclerotic ischemic stroke or Moyamoya disease, Development of medical devices for ischemic stroke

Department of Neurology (임상)