약학대학 전임교수 목록

교수진/연구실
교수진
전임교수

교수정보의 상세 화면-2019
이름 박상규 학력 박사 전공 약학전공(과)
정보	연구실 : 약학관 307호 연구실번호 : 3453 이메일 : sgpark@ajou.ac.kr 연구관심분야 : Stem Cells/Cancer/Drug Development 홈페이지1 : http://www.genefunctionlab.com
학력	졸업연도/학교/학위 2005.02 서울대학교 박사
경력	2007~2009 Assistant professor, Clinical Research Institute, Seoul National University Hospital 2009.09~2014.09 Adjunctive professor, Graduate School of Convergence Science and Technology, Seoul National University 2009~2014.08 Associate professor, Department of Biomedical Science, College of Life Science, CHA University 2014.09~present Associate professor, Dept.of Pharmacy, College of Pharmacy, AJOU University
연구분야	Function Hunting of Med28 Med28 was recently identified as a mediator of transcription complex, which involved in tumorigenesis including breast cancer, prostate cancer. However, its molecular mechanism is not understood. So we isolated binding candidates of med28, and are trying to unveil the molecular mechanism. Many candiates are shown to be associated with cancer progression such as DNA repair, chromosome segregation, suppressor of tumor suppressor, cell-cell signaling. Thus we are studying about the novel regulatory mechanism in cancer onset and progression. p43/AIMP1 and Stem Cell p43/AIMP1 has been known as a multi-functional protein, which take part in immune cell activation, angiogenesis, blood glucose regulation, and wound healing as a cytokine. In addition, p43/AIMP1 regulates TGFb signaling and autoimmune disease in cytoplasm. Interestingly, whole body knock-out of p43/AIMP1 in mouse shows multiple phenotypes including defect of uterus development, petite, ataxia and so on... Thus we generated conditional knock-out mouse to remove p43/AIMP1 tissue specifically. In addition, we are investigating whether the p43/AIMP1 could regulate stem cell mobilization from bone marrow, self-renewal, and differentiation of bone marrow-derived mesenchynal stem cell or hematopoietic stem cell. Furthermore, we are studying if the p43/AIMP1 would clinically applicable. Development of Stem Cell Mobilizer Many clinicians are trying to treat diseases using stem cell. In some case, stem cells should be isolated from peripheral blood and manipulated in vitro to enrich stem cell. Big problem of in vitro manipulation of stem cell is genetic instability. If the stem cell mobilizer would be available, there could be a large amount of stem cell in peripheral blood. if so, we could minimize the genetic instability in vitro. Thus we are screening chemicals to induce stem cell mobilization. Development of Therapeutic Antibody Currently, we are developing therapeutic antibody, targeting rheumatoid arthritis(RA). Recently, we found that AIMP1 cytokine promoted osteoclastogenesis of macrophages and its level is increased in synovial fluid of RA patients. So we generated monoclonal antibody that neutralizes AIMP1 cytokine, and further developed chimeric antibody, which shows efficient attenuation of arthritis in collagen-induced arthritis mouse model. We developed fully humanized antibody, and are performing preclinical study. We are expecting that the atlizumab would be applicable to human body for the treatment of RA.
논문 및 연구활동	연구활동(주요논문) [논문] 조진구, 이준희, 홍신희, Takayuki Asahara, 김서윤, 김재현, 김철민, 오배준, 윤강준, 이한나, 정석윤, 박상규, 권상모, Tauroursodeoxycholic Acid, a Bile Acid, Promotes Blood Vessel Repair by Recruiting Vasculogenic Progenitor Cells , STEM CELLS , pp.1 -10 (Nov, 2014) [논문] 이택기, 박상규, 김왕균, 김원석, 김지혜, 송승용, 이현주, 조윤경, 최준석, 한준희, 황성주, 성종혁, 송순욱, Isolation of adipose-derived stem cells by using a subfractionation culturing method , EXPERT OPINION ON BIOLOGICAL THERAPY , Vol.14 , No.11 , pp.1551 -1560 (Nov, 2014) [논문] 박상규, 김지혜, 김왕균, 송순욱, 성종혁, Functional Regulation of Adipose-derived Stem Cells by PDGF-D , STEM CELLS , pp.1 -8 (Oct, 2014) [논문] 이경원, 강아영, 김민, 김철민, 백광현, 성종혁, 안병용, 임기환, 정성수, 조진구, 박상규, 박경수, Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.288 , No.46 , pp.32886 -32896 (Nov, 2013) [논문] 김서윤, 손우성, 김철민, 박민철, 윤강준, 이수홍, 차병현, 박상규, ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt , STEM CELLS AND DEVELOPMENT , Vol.22 , No.19 , pp.2630 -2640 (Oct, 2013) 국제학술논문지 [논문] 김광혁, 김진옥, 박상규, A fully human anti‑c‑Kit monoclonal antibody 2G4 inhibits proliferation and degranulation of human mast cells , MOLECULAR AND CELLULAR BIOCHEMISTRY , pp.1 -13 (Jan, 2023) [논문] 심윤희, 엄윤정, 박정양, 서민덕, 박상규, A Novel Antibody-Drug Conjugate Targeting Nectin-2 Suppresses Ovarian Cancer Progression in Mouse Xenograft Models , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -15 (Oct, 2022) [논문] 김광혁, 김진옥, 박지수, 고한직, 박상규, Antibody-immunotoxin Conjugate Using FcBP-mediated Photoconjugation to Treat Cancer , ANTICANCER RESEARCH , pp.3453 -3461 (Jul, 2022) [논문] 이주연, 강민희, 강홍석, 양유연, 윤영찬, 이유진, 이의일, 이정은, 장지은, 정경희, 정지웅, 정혜련, 최지용, 홍순선, 박상규, Comparative analysis of mesenchymal stem cells cultivated in serum free media , SCIENTIFIC REPORTS (May, 2022) [논문] 김광혁, 김진옥, 박정양, 서민덕, 박상규, Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.2264 -11 (Feb, 2022) [논문] 서송이, 김진옥, 김경리, 김율이, 김정웅, 성종혁, 송선화, 안미진, 여영주, 우세준, 정하영, 함민희, 박상규, 서원희, A Fully Human Monoclonal Antibody Targeting cKIT Is a Potent Inhibitor of Pathological Choroidal Neovascularization in Mice , PHARMACEUTICS (Aug, 2021) [논문] 김광혁, 김진옥, 고한직, 박보미, 백은지, 고병준, 소민경, 박상규, A novel anti-c-Kit antibody-drug conjugate to treat wild-type and activating-mutant c-Kit-positive tumors , MOLECULAR ONCOLOGY (Aug, 2021) [논문] 여영주, 박상규, 김경리, 김률이, 김정민, 서송이, 성종혁, 이은희, 조은경, 서원희, FGF12 (Fibroblast Growth Factor 12) Inhibits Vascular Smooth Muscle Cell Remodeling in Pulmonary Arterial Hypertension , HYPERTENSION , pp.1778 -1786 (Dec, 2020) [논문] 김진옥, 김하늘, 김광혁, 박정양, 백은지, 하경수, 허덕림, 박상규, 서민덕, Development and characterization of a fully human antibody targeting SCF/c-kit signaling , INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , pp.1 -48 (May, 2020) [논문] 김경리, 박상규, Yeongju Yeo, 김원, 김재택, 김지택, 서송이, 성종혁, 서원희, SCF (Stem Cell Factor) and cKIT Modulate Pathological Ocular Neovascularization , ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (Aug, 2019) [논문] 김진옥, 문진희, 노희동, 고은희, 김수정, 김태성, 박용범, 안성수, 윤태준, 정학준, 박상규, 이상원, Atializumab, a humanized anti-aminoacyl-tRNA synthetases-interacting multifunctional protein-1 (AIMP1) antibody significantly improves nephritis in (NZB/NZW) F1 Mice Biomaterials , BIOMATERIALS (Aug, 2019) [논문] 김진옥, 안성수, 박용범, 송정식, 윤태준, 박상규, 이상원, Serum aminoacyl-tRNA synthetase-interacting multifunctional protein-1 can predict severe antineutrophil cytoplasmic antibody-associated vasculitis: a pilot monocentric study , BIOMED RESEARCH INTERNATIONAL (May, 2019) [논문] 조진구, 최준석, 김진옥, 김홍숙, 노희동, 이재호, 임기환, 조민국, 박병준, 박상규, MED28 over-expression shortens the cell cycle and induces genomic instability , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Apr, 2019) [논문] 김석호, 김형수, 박영준, 홍신희, 김진희, 서원희, 성종혁, 이경원, 임창진, 정기원, 박상규, 박경수, MD001, a Novel Peroxisome Proliferator-activated Receptor α/γ Agonist, Improves Glucose and Lipid Metabolism , SCIENTIFIC REPORTS , pp.1 -12 (Feb, 2019) [논문] 류지연, 조은이, 박상규, 이한아름, 홍신희, 박혜선, 홍관수, 김홍표, 윤태종, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes , Journal of Nanobiotechnology , pp.19 -31 (Jan, 2019) [논문] 홍신희, 안성수, 박용범, 박윤희, 이상원, 정승민, 제이슨 송 정식, 박상규, Serum aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1), a novel disease activity predictive biomarker of systemic lupus erythematosus. , CLINICAL AND EXPERIMENTAL RHEUMATOLOGY , Vol.36 , No.4 , pp.533 -539 (Jul, 2018) [논문] 권성률, 박상규, 김은주, 박헌용, 반원진, 서영식, 임현아, 조용기, 정동근, Effects of the generated functional groups by PECVD on adhesiveness of adipose derived mesenchymal stem cells , JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A , Vol.36 , No.3 (May, 2018) [논문] 조진구, 임기환, 박상규, MED28 increases the colony-forming ability of breast cancer cells by stabilizing the ZNF224 protein upon DNA damage , ONCOLOGY LETTERS , Vol.15 , No.3 , pp.3147 -3154 (Mar, 2018) [논문] 이명석, Youn christine, 김영덕, 김정형, 박병준, 신영기, 안종찬, 홍성렬, 박상규, Enhanced cell growth of adipocyte-derived mesenchymal stem cells using chemically-defined serum-free media , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Aug, 2017) [논문] 장수아, 박상규, 김어수, 김은우, 김철훈, 박민선, 손보경, 윤강준, 이정영, 이정호, 정지헌, 남궁기, Suppression of AIMP1 protects cognition in Alzheimer's disease model mice 3xTg-AD , NEUROREPORT , pp.1 -5 (Nov, 2016) [논문] 홍신희, 엄윤정, 임기환, 조진구, 윤강준, 조영준, 박상규, Tauroursodeoxycholic acid improves viability of artificial RBCs , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , pp.1682 -1687 (Sep, 2016) [논문] 송선화, 박상규, 권진숙, 김경종, 김영욱, 김지택, 배선식, 성종혁, 조은경, 서원희, Fibroblast Growth Factor 12 is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate , ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY , pp.1928 -1936 (Sep, 2016) [논문] 김지혜, 박상규, 김원석, 박인국, 송순욱, 윤세미, 이진우, 성종혁, Hypoxia Suppresses Spontaneous Mineralization and Osteogenic Differentiation of Mesenchymal Stem Cells via IGFBP3 Up-Regulation , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -15 (Aug, 2016) [논문] 조진구, 김홍숙, 임기환, 노태영, 박세호, 서원희, 성종혁, 송승용, 임채현, 함석진, 박상규, ZNF224, Kruppel like zinc finger protein, induces cell growth and apoptosis-resistance by down-regulation of p21 and p53 via miR-663a , ONCOTARGET , pp.31177 -31190 (May, 2016) [논문] 조혜은, 박상규, 강태진, 김지천, 최준석, 심영기, Identification of diagnostic biomarkers for early detection of anthrax from human aortic endothelial cells , INTERNATIONAL JOURNAL OF NANOTECHNOLOGY , pp.413 -425 (May, 2016) [논문] 김소라, 박상규, 김지연, 김지택, 성종혁, 우세준, 임지은, 정지훈, 서원희, The cKit Inhibitor, Masitinib, Prevents Diabetes-Induced Retinal Vascular Leakage , INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE , pp.1201 -1206 (Mar, 2016) [논문] Hemant Kumar, 안종찬, Yopshie Arai, 박세아, 차병현, 한인보, 박상규, 이수홍, AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal , CELL DEATH & DISEASE -12 (Feb, 2016) [논문] 안종찬, 김광일, 김기진, 손미권, 이수홍, 정경희, 박상규, 홍순선, Aminoacyl-tRNA synthetase interacting multi-functional protein 1 attenuates liver fibrosis by inhibiting TGFβ signaling , INTERNATIONAL JOURNAL OF ONCOLOGY , Vol.48 , No.2 , pp.747 -755 (Feb, 2016) [논문] Sireewan Kaewsuwan, 조진구, Anuchit Plubrukarn, Jin?Hyun Jeong, Maleeruk Utsintong, Seok?Ho Kim, 박상규, Jong?Hyuk Sung, Interruptin B induces brown adipocyte differentiation and glucose consumption in adipose-derived stem cells , MOLECULAR MEDICINE REPORTS , pp.1 -9 (Jan, 2016) [논문] 임기환, 박상규, Transcriptional regulation of KRAB-ZFPs in cancer , MOLECULAR & CELLULAR TOXICOLOGY , Vol.11 , pp.389 -394 (Dec, 2015) [논문] 최준석, 박상규, 김예슬, 김준기, 김필한, 양윤정, 이대호, 조은영, 최진우, Identification of cromolyn sodium as an anti-fibrotic agent targeting both hepatocytes and hepatic stellate cells , PHARMACOLOGICAL RESEARCH , Vol.102 , pp.176 -183 (Dec, 2015) [논문] 임기환, 박상규, 구본희, 김진옥, 박장준, 백광현, HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response , SCIENTIFIC REPORTS , Vol.5 , No.12793 , pp.12793(1) -12793(12) (Aug, 2015) [논문] 홍신희, 조진구, 김철훈, 윤강준, 이상원, 임대석, 박상규, The antibody atliximab attenuates collagen-induced arthritis by neutralizing AIMP1, an inflammatory cytokine that enhances osteoclastogenesis , BIOMATERIALS , Vol.44 , pp.45 -54 (Mar, 2015) [논문] 유민아, 조진구, 김광일, 성종혁, 양호빈, 조영준, 박상규, Generation of Med28 Specific Monoclonal Antibodies , MONOCLONAL ANTIBODIES IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY , Vol.34 , No.1 , pp.30 -35 (Feb, 2015) [논문] 조진구, 이준희, 홍신희, Takayuki Asahara, 김서윤, 김재현, 김철민, 오배준, 윤강준, 이한나, 정석윤, 박상규, 권상모, Tauroursodeoxycholic Acid, a Bile Acid, Promotes Blood Vessel Repair by Recruiting Vasculogenic Progenitor Cells , STEM CELLS , pp.1 -10 (Nov, 2014) [논문] 이택기, 박상규, 김왕균, 김원석, 김지혜, 송승용, 이현주, 조윤경, 최준석, 한준희, 황성주, 성종혁, 송순욱, Isolation of adipose-derived stem cells by using a subfractionation culturing method , EXPERT OPINION ON BIOLOGICAL THERAPY , Vol.14 , No.11 , pp.1551 -1560 (Nov, 2014) [논문] 박상규, 김지혜, 김왕균, 송순욱, 성종혁, Functional Regulation of Adipose-derived Stem Cells by PDGF-D , STEM CELLS , pp.1 -8 (Oct, 2014) [논문] 권용수, 윤영일, 박상규, 김영일, 박경순, 안국준, 이수홍, 제환준, 조영석, 조희상, 허선희, 황승일, 윤태종, 이학종, 이학호, Ultrasound-mediated gene and drug delivery using a microbubble-liposome particle system , THERANOSTICS , Vol.4 , No.11 , pp.1133 -1144 (Sep, 2014) [논문] 박미리, 정지혜, 박상규, Haengseok Song, 고정재, 김혜련, 박미선, 이동률, 임은진, 최은, 홍권호, 최영석, The expression of aminoacyl-tRNA-synthetase-interacting multifunctional protein-1 (Aimp1) is regulated by estrogen in the mouse uterus , MOLECULAR AND CELLULAR ENDOCRINOLOGY , Vol.5 , No.399 , pp.78 -86 (Aug, 2014) [논문] Lina Jia, 이훈석, 박상규, Chun Fu Wu, Juthika Kundu, Ozgur Cem Erkin, 김용남, 양호빈, 왕리휘, 채승완, 최윤라, 최종선, 신영기, SMAD4 suppresses AURKA-induced Metastatic Phenotypes via Degradation of AURKA in a TGF-beta-independent manner , MOLECULAR CANCER RESEARCH (Jul, 2014) [논문] 김왕균, 김지혜, 박상규, 곽미희, 김대덕, 서현민, 성영관, 송승용, 이택기, 이현주, 최준석, 성종혁, 송순욱, The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells , STEM CELLS AND DEVELOPMENT , Vol.23 , No.12 , pp.1364 -1376 (Jun, 2014) [논문] 차병현, 박상규, 김병수, 김진수, 김희천, 안종찬, 한동근, 이수홍, The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress , BIOMATERIALS , Vol.35 , No.9 , pp.2851 -2858 (Mar, 2014) [논문] 이경원, 강아영, 김민, 김철민, 백광현, 성종혁, 안병용, 임기환, 정성수, 조진구, 박상규, 박경수, Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.288 , No.46 , pp.32886 -32896 (Nov, 2013) [논문] 김서윤, 손우성, 김철민, 박민철, 윤강준, 이수홍, 차병현, 박상규, ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt , STEM CELLS AND DEVELOPMENT , Vol.22 , No.19 , pp.2630 -2640 (Oct, 2013) [논문] 박상규, 김지혜, 김진경, 송승용, 성종혁, Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2 , CELL DEATH & DISEASE , Vol.4 (Apr, 2013) [논문] 강태희, 김규엽, 박상규, 조영준, Convergent evolution of two different random RNAs for specific interaction with methionyl-tRNA synthetase , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.432 , No.2 , pp.281 -286 (Mar, 2013) 국제학술발표 [학술회의] 박상규, Development of Antibody-drug congugate for SCLC and GIST , 2023 international conference of the Korean Society of Pharmaceuticla Sciences and Technology (Dec, 2023) [학술회의] 박상규, Strategy for ADC development , 2023 대한약학회 춘계국제학술대회 (Apr, 2023) [학술회의] 엄윤정, 박상규, Payload screening for antibody-drug conjugate development targeting CDCP1 , 2022 대한약학회 추계국제학술대회 , pp.602 -602 (Oct, 2022) [학술회의] 심윤희, 박상규, 엄윤정, A novel antibody-drug conjugate targeting nectin-2 suppresses ovarian cancer progression in mouse xenograft models , 2022 대한약학회 추계국제학술대회 , pp.357 -357 (Oct, 2022) [학술회의] 김광혁, 박상규, A fully human anti-c-Kit antibody 2G4 inhibits growth and function of human mast cell , 2022 대한약학회 추계국제학술대회 , pp.552 -552 (Oct, 2022) [학술회의] 박상규, Development of Antibody-Drug ConjugateTargeting c-Kit to Treat Cancer , Antibody Society Korea 2021 Summer Conference (Jul, 2021) [학술회의] 심윤희, 박상규, 엄윤정, Development of Antibody-Drug Conjugate Targeting Nectin-2 to Treat Ovarian Cancer , 2021 대한약학회 온라인 춘계국제학술대회 , pp.516 -516 (Apr, 2021) [학술회의] 김진옥, 박상규, Development of Antibody Drug Conjugate Targeting c-Kit and Validation of Effectiveness in Cancer , 2020 생화학분자생물학회 International eConference (Sep, 2020) [학술회의] 김진옥, 박상규, 김광혁, Development of Full Human Antibody Targeting c-Kit and its Application to Treat cancer , American Association for Cancer Research (AACR) Virtual Annual Meeting (Jun, 2020) [학술회의] 김진옥, 박상규, 김광혁, Development of Full Human Antibody Targeting c-Kit and its Application to Treat Cancer , 생화학분자생물학회 동계학술대회 (Jan, 2020) [학술회의] 김석호, 박상규, 김광혁, 김진옥, Identification and Characterization of a Novel Peroxisome Proliferator-Activated Receptor α/γ agonist for the Treatment of Metabolic Disease , 2018 추계 약학회 국제학술대회 (Oct, 2018) [학술회의] 박상규, Development of therapeutic antibody for Rheumatoid arthritis , 2018 춘계 국제 약학회 (Apr, 2018) [학술회의] 임기환, 박상규, 엄윤정, 조진구, Shortening the cell cycle by MED28, mediator complex subunit, modulates aneuploidy in the breast adenocarcinoma , 한국 생화학분자생물학회 제8회 동계학술대회 (Jan, 2017) [학술회의] 홍신희, 박상규, Identification of Novel therapeutic target for arthritis treatment , 2016 International Conference of The Korean Society of Pharmaceutical Sciences and Technology (2016 한국약제학회 국제학술대회) (Dec, 2016) [학술회의] 홍신희, 박상규, Tauroursodeoxycholic Acid increases Viability of CD34+-derived Red Blood Cells , 대한약학회 70주년 국제학술대회 (Oct, 2016) [학술회의] 조진구, 박상규, ZNF224 promotes tumor growth : Identification of Novel Pathway , 대한약학회 70주년 국제학술대회 (Oct, 2016) [학술회의] 박상규, Antibody Therapeutics targeting Rheumatoid Arthritis , 2015 2nd International Symposium (Developing trends of a medicine for rare or obstinate disease and globalization) (Nov, 2015) [학술회의] 유민아, 박상규, Development and characterizaiton of human Med28 Specific Monoclonal Antibodies , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 조진구, 박상규, ZNF224 decreases p53 and p21 via MIR663A , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 조진구, 박상규, Tauroursodeocycholic acid, bile acid, induces blood vessel repair via stem cell mobilization , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 홍신희, 박상규, 조진구, Effect of ARS-interacting multi-functional protein 1 (AIMP1) antibody on collagen-induced arthritis , Frontiers in Stem Cells & Cancer (Mar, 2015) 국내학술발표 [학술회의] 박상규, Antibody-drug conjugate for cancer treatment , 2023 제 8회 High1 신약개발 심포지아 (Jan, 2023) [학술회의] 김광혁, 박상규, therapeutic efficacy of anti-c-Kit antibody drug conjugate against cancer cells having both wild-type and mutant c-Kit , 2021년 한국통합생물학회 정기학술대회 (Dec, 2021) [학술회의] 박상규, antibody-drug conjugate to treat cancer , 2021년 한국통합생물학회 정기학술대회 (Dec, 2021) [학술회의] 심윤희, 박상규, Evaluation of efficacy of antibody-drug conjugate against Nectin-2 , 2021년 한국통합생물학회 정기학술대회 (Dec, 2021) [학술회의] 박상규, Development of Serum free chemically defined media for stem cell therapeutics , 2018 생명약학연구회-한국약제학회 동계 심포지움 (Feb, 2018) [학술회의] 조진구, 박상규, 임기환, MED28 increases the colony-forming ability of breast cancer cells by stabilizing the ZNF224 protein upon DNA damage , 통합생물학회 (Dec, 2017) [학술회의] 엄윤정, 박상규, 임기환, 홍신희, Characterizing and Generating of Monoclonal Antibody for Targeting α isoform Nectin-2 , 한국 생화학분자생물학회 제 8회 동계학술대회 (Jan, 2017) [학술회의] 박상규, First-in-class antibody development for rheumatoid arthritis , 제3회 아주대학교 의약학 공동심포지엄 (Nov, 2016) [학술회의] 박상규, AIMP1, a Novel Target for Arthritis , 2016년 생명약학 연구회 하계 심포지엄 (Jul, 2016) [학술회의] 박상규, Application of AIMP1 for Chondrogenic Differentiation , 약품생화학분자생물학분과 하계심포지엄 (Jun, 2016) [학술회의] 박상규, 중간엽 줄기세포의 효율적 배양기술 , 한국조직공학재생의학회 교육심포지엄 (Nov, 2015) [학술회의] 박상규, AIMP1을 타겟으로하는 류마티스성 관절염 치료용 항체 개발 , 치료용 단백질 개발 심포지움 (Jan, 2015) [학술회의] 박상규, 조진구, 홍신희, 권상모, Tauroursodeocycholic acid, bile acid, induces blood vessel repair , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) [학술회의] 홍신희, 박상규, 조진구, The AIMP1 neutralizing antibody attenuates collagen-induced arthritis , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) [학술회의] 유민아, 박상규, 조진구, Development of Med28 Specific Monoclonal Antibodies , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) 저서 및 번역 [저서] 박상규, 약품생화학 분자생물학 총정리 , pp.139~154 (Oct, 2015)
특허 및 기타	[특허] 박상규, 김광혁, 비만세포 활성화 장애의 예방 또는 치료용 항체 (출원) (10-2021-0133123) (Oct, 2021) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (등록) (6835983) (R0420JP) (Feb, 2021) [특허] 박상규, 김광혁, 김진옥, c-kit에 대한 항체 및 이의 용도 (출원) (10-2019-0152304) (Nov, 2019) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (16/608,931) (R0420US) (Oct, 2019) [특허] 박상규, 손미권, 홍순선, 간질환 예방 또는 치료용 펩타이드 발명의 명칭 및 이를 유효성분으로 포함하는 조성물 (등록) (10-1996490) (Jun, 2019) [특허] 박상규, 유방암 예후 예측용 바이오마커 (등록) (10-1943157) (Jan, 2019) [특허] 박상규, PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 (등록) (10-1934197) (Dec, 2018) [특허] 박상규, 김진옥, c-kit 항체 개발 (출원) (10-2018-0120233) (Oct, 2018) [특허] 박상규, PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 (출원) (PCT/KR2018/006649) (Jun, 2018) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (PCT/KR2018/005001) (Apr, 2018) [특허] 박상규, 조진구, 홍신희, ＴＵＤＣＡ를 이용한 줄기세포 생물작용 활성 증가, 및 이를 포함하는 줄기세포 치료 보조제 (등록) (9,896,662) (R0420US) (Feb, 2018) [특허] 박상규, SCF를 중화하는 단일클론 항체 (출원) (10-2017-0143816) (Oct, 2017) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (10-2017-0055247) (Apr, 2017)

빠른 이동 메뉴